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Is it OK to buy that puppy????
Posted on 16 December, 2014 at 12:17 |
Categories: animal welfare, Current Issues, INFORMATIVE ARTICLES
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college essaywriting
4:34 on 12 October, 2016
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tcsgroupk
7:07 on 27 January, 2022
carmustine (bis-chloroethylnitrosourea, bcnu, bicnu) is a medication used mainly for chemotherapy. it is a nitrogen mustard ß-chloro-nitrosourea compound used as an alkylating agent.
description
carmustine is an orange-yellow solid medication used mainly for chemotherapy. it is a nitrogen mustard ß-chloro-nitrosourea compound.
mechanism of action
as an alkylating agent, carmustine can form interstrand crosslinks in dna, which prevents dna replication and dna transcription.[citation needed]
uses
carmustine is used as an alkylating agent to treat several types of brain cancer including glioma, glioblastoma multiforme, medulloblastoma and astrocytoma), multiple myeloma, and lymphoma (hodgkin's and non-hodgkin).
bcnu is sometimes used in conjunction with alkyl guanine transferase (agt) inhibitors, such as o6-benzylguanine. the agt-inhibitors increase the efficacy of carmustine by inhibiting the direct reversal pathway of dna repair, which will prevent formation of the interstrand crosslink between the n1 of guanine and the n3 of cytosine.
it is also used as part of a chemotherapeutic protocol in preparation for hematological stem cell transplantation, a type of bone marrow transplant, in order to reduce the white blood cell count in the recipient. use under this protocol, usually with fludarabine and melphalan, was developed by oncologists at the university of texas md anderson cancer center.[citation needed]
description
carmustine is an orange-yellow solid medication used mainly for chemotherapy. it is a nitrogen mustard ß-chloro-nitrosourea compound.
mechanism of action
as an alkylating agent, carmustine can form interstrand crosslinks in dna, which prevents dna replication and dna transcription.[citation needed]
uses
carmustine is used as an alkylating agent to treat several types of brain cancer including glioma, glioblastoma multiforme, medulloblastoma and astrocytoma), multiple myeloma, and lymphoma (hodgkin's and non-hodgkin).
bcnu is sometimes used in conjunction with alkyl guanine transferase (agt) inhibitors, such as o6-benzylguanine. the agt-inhibitors increase the efficacy of carmustine by inhibiting the direct reversal pathway of dna repair, which will prevent formation of the interstrand crosslink between the n1 of guanine and the n3 of cytosine.
it is also used as part of a chemotherapeutic protocol in preparation for hematological stem cell transplantation, a type of bone marrow transplant, in order to reduce the white blood cell count in the recipient. use under this protocol, usually with fludarabine and melphalan, was developed by oncologists at the university of texas md anderson cancer center.[citation needed]
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- Welcome
- Get to know OCPAW
- Contact Information
- Our Donors
- Topsail Times Newspaper Articles
- Honor your Pet on the Rainbow Bridge Memoriam Page
- Enter & Vote 2022 Hero Dog Awards
- Letter from a Shelter Manager....
- Hand-raising kittens: What to expect.
- Adoption Application
- Rehoming Pet Information
- Feral Spay/Neuter Application & Drop Trap Program
- Spay/Neuter Application
- Nominate Your Vet or Vet Nurse/Tech for the Hero Awards
- List of Vets & Join our Vet Network
- Veterinary Payment Request for Vouchers
- Don't shop, Adopt.
- Effectively treat fleas.
- Parvo:What you need to know
- Service dog to Surf-ice dog!
- Legal Disclaimer & Privacy Policy
- Request Assisstance
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